Related Experiment Video
Updated: Jun 17, 2026

Murine Distal Colostomy, A Novel Model of Diversion Colitis in C57BL/6 Mice
Published on: July 12, 2018
Colonic diverticulosis and diverticular hemorrhage
Justin A Maykel1, Frank G Opelka
1Department of Surgery, Beth Israel Deaconess Medical Center, Boston, MA 02215-5491, USA.
Colonic diverticulosis can cause lower gastrointestinal bleeding. Diagnosis and control involve colonoscopy, angiography, or nuclear scintigraphy, with surgery as a last resort for persistent hemorrhages.
Area of Science:
- Gastroenterology
- Colorectal Surgery
Background:
- Colonic diverticulosis affects up to 5% of individuals, potentially leading to lower gastrointestinal hemorrhage.
- Diverticular disease involves sac-like pseudodiverticula formation influenced by anatomical, dietary, and motility factors.
Purpose of the Study:
- To outline the diagnostic and therapeutic strategies for managing lower gastrointestinal hemorrhage secondary to colonic diverticulosis.
Main Methods:
- Review of diagnostic modalities including colonoscopy, angiography, and nuclear scintigraphy for hemorrhage localization.
- Discussion of interventional and surgical approaches for hemorrhage control.
Main Results:
- Most diverticular bleeds can be localized and controlled using endoscopic or angiographic techniques.
- Persistent bleeding unresponsive to non-surgical interventions requires surgical resection.
Conclusions:
- Prompt patient stabilization is crucial in acute diverticular hemorrhage.
- A multi-modal approach combining diagnostic imaging and interventions effectively manages diverticular bleeding.
- Surgical resection remains the definitive treatment for intractable cases.
Related Concept Videos
Diverticular Disease of the Colon
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory Bowel Disease I: Introduction
Inflammatory Bowel Disease II: Ulcerative Colitis
Inflammatory Bowel Disease IV: Clinical Manifestations
Inflammatory Bowel Disease II: Crohn's Disease
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
