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Published on: April 17, 2019
[A clinico-anatomical correlation study of logorrhoea]
A Robles-Bayón1, D Santos-García, X Rodríguez-Osorio
1Unidad de Neurología Cognitiva, Hospital La Rosaleda, Santiago de Compostela, E-15701 Santiago de Compostela (A Coruña), Espana. alfredorobles@hospitalrosaleda.com
Logorrhoea, characterized by excessive talking, is linked to frontotemporal degeneration. Brain imaging reveals alterations in the anterior temporal lobes, particularly the right side, in patients with this condition.
Area of Science:
- Neuroscience
- Neurology
- Speech Pathology
Context:
- Logorrhoea (excessive verbal production) lacks a defined threshold and clear neuroanatomical correlates.
- Understanding the neurobiology of logorrhoea is crucial for diagnosis and treatment.
Purpose:
- To quantify normal oral verbal production.
- To identify the brain regions associated with logorrhoea in patients.
Summary:
- Oral verbal production was quantified in 60 controls; education level influenced output.
- Ten patients with logorrhoea underwent neuroimaging, revealing frontotemporal degeneration.
- Cortical atrophy was consistently observed in the anteromedial and anteroinferior regions of the right anterior temporal lobes.
Impact:
- Establishes quantitative benchmarks for normal verbal production.
- Links logorrhoea to specific neuroanatomical alterations in frontotemporal degeneration.
- Provides insights for diagnosing and potentially treating logorrhoea.
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