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Updated: Jun 17, 2026
05:31
Murine Model of Thoracic Aortic Dissection Induced by Oral β-Aminopropionitrile and Subcutaneous Angiotensin II Infusion
Published on: May 16, 2025
[Aortic disease in women]
1Service d'angiologie et d'hémostase, Hôpitaux universitaires de Genève, 24 rue Micheli-du-Crest, Genève, CH 1211, Suisse. francois.becker@wanadoo.fr
Presse Medicale (Paris, France : 1983)
|December 18, 2009
Summary
Abdominal aortic aneurysms (AAA) in women are less common but grow faster and rupture more often than in men. Early screening and risk factor management are crucial for women
Area of Science:
- Vascular surgery
- Cardiology
- Women's health
Context:
- Abdominal aortic disease (AAD) in women is predominantly atheromatous, unlike inflammatory conditions.
- Intramural hematomas and atheromatous ulcers affect men and women equally, with varied outcomes.
- Atherosclerotic stenoses at the aortoiliac bifurcation are rising in young women, linked to smoking.
Purpose:
- To highlight the unique characteristics of abdominal aortic aneurysms (AAA) in women.
- To emphasize the increased rupture risk and faster growth rate of AAA in women compared to men.
- To underscore the importance of tailored diagnostic and surgical criteria for women, considering aortic size and cardiovascular comorbidities.
Summary:
- AAA are less frequent in women but exhibit accelerated growth and higher rupture risk.
- Key risk factors for AAA in women include family history and smoking.
- Current guidelines recommend AAA screening for specific high-risk women populations based on age, family history, and lifestyle factors.
- Comprehensive management of modifiable risk factors is essential for patients with small AAA to reduce cardiovascular and surgical risks.
Impact:
- Recognizing women's specific AAA risk factors and presentation is vital for timely diagnosis and intervention.
- Tailored screening protocols can improve early detection rates in at-risk women.
- Effective management of modifiable risk factors can mitigate cardiovascular and surgical risks, improving outcomes for women with AAA.
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