Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Dose-Response Relationship: Potency and Efficacy01:22

Dose-Response Relationship: Potency and Efficacy

The potency of a drug is the measure of its ability to produce a biological response and can be compared by looking at the half-maximum effective concentration or EC50 values of different drugs. A lower EC50 value indicates higher potency of the drug. In the dose–response curve of two antihypertensive drugs, candesartan and irbesartan, a significant difference is observed in their EC50 values. A lower EC50 value for candesartan indicates that it is more potent than irbesartan, as it produces...
Dose-Response Relationship: Overview01:03

Dose-Response Relationship: Overview

Agonists can bind with and activate receptors, resulting in the formation of drug-receptor complexes. Once formed, these complexes catalyze many biochemical processes at the cellular level and subsequently induce a pharmacologic response. The degree of response is directly proportional to the fraction of activated receptors, which in turn, depends on the concentration of the drug at the receptor site as well as the sensitivity of the receptor. An increase in the administered dose contributes to...
Exercise and Cardiovascular Response01:20

Exercise and Cardiovascular Response

Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Exercise and Muscle Performance01:27

Exercise and Muscle Performance

Exercise induces a range of adaptations in muscle tissue, depending on the type and duration of activity. Such physical training can be broadly categorized into two types: endurance exercises and resistance exercises.
Endurance exercises
Endurance exercises involve running, swimming, or cycling, which require repetitive movements with low force output. When a person engages in endurance exercise, a few noticeable changes occur in their skeletal muscles. For instance, the number of capillaries...
Dose-Response Relationship: Selectivity and Specificity01:25

Dose-Response Relationship: Selectivity and Specificity

Drugs exert their therapeutic effects by interacting with receptors, enzymes, or ion channels that are present throughout the human body. The strength and duration of the interaction between a drug and its target receptor are characterized by the selectivity and specificity of the drug. Selectivity refers to a drug's strong preference for its intended target over other targets. For instance, isoprenaline, a non-selective β-adrenergic agonist, interacts with both β1- and β2-adrenergic receptors...
Pharmacokinetic–Pharmacodynamic Relationship: Intensity of Dose-Effect Relationship01:23

Pharmacokinetic–Pharmacodynamic Relationship: Intensity of Dose-Effect Relationship

Pharmacodynamics explores the relationship between drug concentration and its effect. In a quantal response drug, the duration of action better correlates with drug concentration, while for graded effect drugs, the intensity of response is more relevant. This intensity depends on the dose, drug removal rate, and the region of the concentration–response curve.The concentration–response curve can be divided into three regions. Region 3 (80–100% maximum response) demonstrates that even as drug...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

APOE-ε4 moderates the association between diet quality and executive function in middle-aged women at increased risk for Alzheimer's disease.

Journal of nutritional science·2026
Same author

From Fitness to Cognition: Machine-Learning Prediction of Cognitive Performance Using Physiological Parameters in Healthy Adults.

Medicine and science in sports and exercise·2026
Same author

The Relationship Between Physical Activity and Facial Affect Recognition in Older Adults Versus Younger Adults.

Journal of sport & exercise psychology·2026
Same author

Effects of aerobic exercise on core executive function in adults with major depressive disorder: A Systematic review and three-level meta‑analysis.

Psychiatry research·2026
Same author

Global Trends in Tai Chi Research: A Bibliometric Analysis.

Sports (Basel, Switzerland)·2026
Same author

The relationship between mindfulness, competitive anxiety, and self-efficacy in Taekwondo athletes with/without injury: The moderated mediation model.

Psychology of sport and exercise·2026
Same journal

Indigenized Science.

Journal of sport & exercise psychology·2026
Same journal

The Power of Togetherness in Physical Education: Relationship Between Class Cohesion, Engagement, Disruptive Behaviors, and Perceived Academic Performance.

Journal of sport & exercise psychology·2026
Same journal

Digest.

Journal of sport & exercise psychology·2026
Same journal

Mindful Sport Performance Enhancement in Youth Soccer: A Randomized Active-Control Trial of Objective Performance Under Pressure and Psychological Outcomes.

Journal of sport & exercise psychology·2026
Same journal

Lay Beliefs About the Impact of Reminiscing About Sport Milestones on Future Performance.

Journal of sport & exercise psychology·2026
Same journal

Exploring the Viability of Encouraging Person-Adaptive Exercise During a 2-Week Microcycle: A Mixed-Method Study of Flexible Nonlinear Periodization.

Journal of sport & exercise psychology·2026
See all related articles

Related Experiment Video

Updated: Jun 17, 2026

Orienteering as a Tool for Cognitive Research: An Implementation Guide
07:13

Orienteering as a Tool for Cognitive Research: An Implementation Guide

Published on: November 29, 2024

Exploring the dose-response relationship between resistance exercise intensity and cognitive function.

Yu-Kai Chang1, Jennifer L Etnier

  • 1Graduate Institute of Coaching Sciences, National Taiwan Sport University, Taoyuan, Taiwan (Republic of China).

Journal of Sport & Exercise Psychology
|December 18, 2009
PubMed
Summary
This summary is machine-generated.

Resistance exercise intensity impacts cognitive function differently based on intensity. High-intensity exercise boosts processing speed, while moderate intensity best enhances executive function, revealing a clear dose-response relationship.

More Related Videos

Randomized Controlled Trial to Study the Acute Effects of Strength Exercise on Insulin Sensitivity in Obese Adults
06:13

Randomized Controlled Trial to Study the Acute Effects of Strength Exercise on Insulin Sensitivity in Obese Adults

Published on: December 1, 2023

Related Experiment Videos

Last Updated: Jun 17, 2026

Orienteering as a Tool for Cognitive Research: An Implementation Guide
07:13

Orienteering as a Tool for Cognitive Research: An Implementation Guide

Published on: November 29, 2024

Randomized Controlled Trial to Study the Acute Effects of Strength Exercise on Insulin Sensitivity in Obese Adults
06:13

Randomized Controlled Trial to Study the Acute Effects of Strength Exercise on Insulin Sensitivity in Obese Adults

Published on: December 1, 2023

Area of Science:

  • Exercise Physiology
  • Cognitive Neuroscience
  • Sports Science

Background:

  • Understanding the relationship between physical activity and cognitive function is crucial for public health.
  • Resistance exercise is a key component of physical fitness, but its specific effects on cognition require further elucidation.
  • Dose-response relationships are fundamental in physiology, guiding optimal exercise prescription.

Purpose of the Study:

  • To investigate the dose-response relationship between resistance exercise intensity and cognitive performance.
  • To determine how varying intensities of resistance exercise affect different cognitive domains.
  • To identify optimal exercise intensities for specific cognitive benefits.

Main Methods:

  • Sixty-eight participants were randomized into four groups: control, 40%, 70%, or 100% of 10-repetition maximum (10RM) resistance exercise.
  • Cognitive performance was assessed at baseline and post-exercise.
  • Physiological and psychological measures (heart rate, perceived exertion, arousal, affect) were recorded.

Main Results:

  • A significant linear relationship was found between exercise intensity and information processing speed.
  • A significant quadratic trend indicated that exercise intensity affects executive function in a non-linear manner.
  • High-intensity resistance exercise enhanced processing speed, whereas moderate intensity was most beneficial for executive function.

Conclusions:

  • A distinct dose-response relationship exists between resistance exercise intensity and cognitive performance.
  • Exercise intensity should be tailored to target specific cognitive functions for optimal outcomes.
  • These findings have implications for designing exercise programs to enhance cognitive health.