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Drug-induced psychoses.

K M Hurlbut1

  • 1Poison Centre, University of Arizona, Tucson 85724.

Emergency Medicine Clinics of North America
|February 1, 1991
PubMed
Summary
This summary is machine-generated.

Drug-induced psychoses stem from various substances like cocaine and LSD. Management includes supportive care, benzodiazepines, and sometimes specific antidotes, with careful evaluation for other toxic effects.

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Area of Science:

  • Toxicology
  • Psychiatry
  • Pharmacology

Background:

  • Drug-induced psychoses are a significant clinical concern.
  • Numerous substances, including stimulants, hallucinogens, and steroids, can precipitate psychotic episodes.

Purpose of the Study:

  • To outline the primary causes of drug-induced psychoses.
  • To describe the management strategies for these conditions.
  • To emphasize the need for comprehensive toxicological assessment.

Main Methods:

  • Review of major drug classes known to cause psychosis.
  • Description of standard supportive care and pharmacological interventions.
  • Identification of specific antidotes and adjunctive treatments.

Main Results:

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  • Common etiologies include cocaine, amphetamines, phencyclidine, cannabinoids, LSD, and anticholinergic compounds.
  • General management involves supportive measures, sedation with benzodiazepines, and environmental control.
  • Specific interventions like physostigmine or urinary acidification are indicated in select cases.

Conclusions:

  • Prompt identification and management of drug-induced psychosis are crucial.
  • Treatment often requires a combination of supportive care and targeted interventions.
  • Thorough evaluation for co-existing toxic effects is essential for patient safety.