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Simultaneous genome-wide association studies of anti-cyclic citrullinated peptide in rheumatoid arthritis using

Yanzhu Lin1, Min Zhang, Libo Wang

  • 1Department of Statistics, Purdue University, West Lafayette, Indiana 47907, USA. YL: lin43@purdue.edu.

BMC Proceedings
|December 19, 2009
PubMed

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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
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