Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Diabetes: Management and Pharmacotherapy

Diabetes: Management and Pharmacotherapy

The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...

Type II Diabetes I: Introduction

Type II Diabetes I: Introduction

Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by insulin resistance, in which target tissues such as the liver, muscle, and adipose tissue respond poorly to insulin. It is also associated with inadequate compensatory insulin secretion, where pancreatic β-cells fail to produce sufficient insulin. Together, these abnormalities lead to persistent hyperglycemia.EtiologyT2DM develops through a complex interaction of genetic predisposition and environmental or...

Type I Diabetes I: Introduction

Type I Diabetes I: Introduction

Type 1 diabetes mellitus is a chronic metabolic disorder characterized by an absolute deficiency of insulin resulting from the autoimmune destruction of pancreatic β-cells. Although it can occur at any age, it is most commonly diagnosed in childhood, adolescence, or early adulthood. The loss of insulin production impairs cellular glucose uptake, resulting in persistent hyperglycemia and necessitating lifelong insulin therapy.Autoimmune Destruction of β-CellsThe hallmark of type 1 diabetes is an...

Diabetes Mellitus: Introduction

Diabetes Mellitus: Introduction

Diabetes mellitus consists of chronic metabolic disorders characterized by persistent hyperglycemia. This elevated blood glucose results from defects in insulin secretion, impaired insulin action, or both. Insulin, produced by pancreatic β-cells, is essential for maintaining glucose homeostasis by facilitating cellular glucose uptake for energy or storage. Disruptions in insulin production or function lead to glucose accumulation in the bloodstream, causing the clinical features and long-term...

Diabetes Mellitus: Type 2 and Gestational

Diabetes Mellitus: Type 2 and Gestational

Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...

Type II Diabetes II: Pathophysiology

Type II Diabetes II: Pathophysiology

PathophysiologyType 2 diabetes mellitus (T2DM ) is a chronic metabolic disorder characterized by insulin resistance and progressive pancreatic β-cell dysfunction, leading to impaired glucose homeostasis. It results from interactions among genetic predisposition, environmental factors, and metabolic stressors, such as overnutrition and a sedentary lifestyle.Insulin Resistance and Glucose DysregulationEarly T2DM involves insulin resistance in skeletal muscle, adipose tissue, and the liver.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Music interventions with children, adolescents and emerging adults in mental health settings: a scoping review.

Arts & health·2023

Same author

Convergent and Discriminant Validity of Default Mode Network and Limbic Network Perfusion in Amnestic Mild Cognitive Impairment Patients.

Journal of Alzheimer's disease : JAD·2021

Same author

The big one.

British journal of sports medicine·2020

Same author

Age at onset reveals different functional connectivity abnormalities in prodromal Alzheimer's disease.

Brain imaging and behavior·2020

Same author

Spatial separation of the processing and MHC class I loading compartments for cross-presentation of the tumor-associated antigen HER2/<i>neu</i> by human dendritic cells.

Oncoimmunology·2016

Same author

Is the hospital's magnet status linked to HCAHPS scores?

Journal of nursing care quality·2014

Same journal

Correction to 'Competencies for Diabetes Care and Education Specialists' by Ryan et al. <i>The Diabetes Educator</i> 46(4), pages 384-397 (August 2020).

The Diabetes educator·2020

Same journal

<i>The Diabetes Educator</i> (<i>TDE</i>): Successes, Opportunities, and Future Changes.

The Diabetes educator·2020

Same journal

An Umbrella Review of Text Message Programs for Adults With Type 2 Diabetes.

The Diabetes educator·2020

Same journal

Community-Based Participatory Research Interventions to Improve Diabetes Outcomes: A Systematic Review.

The Diabetes educator·2020

Same journal

"Together We Can Return to Balance"-Eastern Woodlands Native Perspectives and Type 2 Diabetes: A Qualitative Study.

The Diabetes educator·2020

Same journal

The Healthy Eating and Living Against Noncommunicable Diseases Study: An Innovative Family-Based Intervention.

The Diabetes educator·2020

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 17, 2026

Effects of Mindfulness Training Combined with Tai Chi in Patients with Diabetic Peripheral Neuropathy

Effects of Mindfulness Training Combined with Tai Chi in Patients with Diabetic Peripheral Neuropathy

Published on: July 14, 2023

Promoting physical activity for persons with diabetes.

Andrea Diedrich¹, Donna J Munroe², Melissa Romano³

¹Mercy Gilbert Medical Center, Gilbert, Arizona (Ms Diedrich)

The Diabetes Educator

|December 19, 2009

Summary

This summary is machine-generated.

A self-help physical activity program using pedometers significantly improved outcomes for type 2 diabetes patients. The intervention group showed reduced hemoglobin A1C, weight, and body fat, alongside increased daily steps.

More Related Videos

Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People

Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People

Published on: July 5, 2017

Glycemic Impact on Knee Osteoarthritis Symptoms on Physical, Radiographic, and Inflammatory Markers among Individuals Aged 50 and Over with Diabetes

Glycemic Impact on Knee Osteoarthritis Symptoms on Physical, Radiographic, and Inflammatory Markers among Individuals Aged 50 and Over with Diabetes

Published on: March 7, 2025

Related Experiment Videos

Last Updated: Jun 17, 2026

Effects of Mindfulness Training Combined with Tai Chi in Patients with Diabetic Peripheral Neuropathy

Effects of Mindfulness Training Combined with Tai Chi in Patients with Diabetic Peripheral Neuropathy

Published on: July 14, 2023

Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People

Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People

Published on: July 5, 2017

Glycemic Impact on Knee Osteoarthritis Symptoms on Physical, Radiographic, and Inflammatory Markers among Individuals Aged 50 and Over with Diabetes

Glycemic Impact on Knee Osteoarthritis Symptoms on Physical, Radiographic, and Inflammatory Markers among Individuals Aged 50 and Over with Diabetes

Published on: March 7, 2025

Area of Science:

Endocrinology
Exercise Physiology
Public Health

Background:

Type 2 diabetes management requires lifestyle interventions.
Physical activity is crucial for improving glycemic control and cardiovascular health in diabetic patients.
Self-help programs offer accessible strategies for behavior change.

Purpose of the Study:

To assess the efficacy of a self-help physical activity intervention for individuals with type 2 diabetes.
To determine the impact of the program on key health indicators including cardiovascular markers, hemoglobin A1c, body composition, and activity levels.

Main Methods:

An intervention study involving 53 participants with type 2 diabetes, randomly assigned to an intervention or control group.
The intervention group received the Diabetes Self-Management Education Program (DSMEP) plus a pedometer and educational materials. The control group received DSMEP only.
Data were collected at baseline and 3 months, utilizing questionnaires and objective physical and anthropometric measurements.

Main Results:

The intervention group exhibited significant reductions in hemoglobin A1c, weight, and body fat, with a notable increase in daily steps.
Both groups showed improvements in hemoglobin A1c, weight, and weekly physical activity levels.
The intervention group achieved significantly lower diastolic blood pressure compared to the control group at study conclusion.

Conclusions:

Pedometers can effectively motivate individuals with type 2 diabetes to increase physical activity.
Participation in the Diabetes Self-Management Education Program (DSMEP) alone may be sufficient to enhance physical activity levels in this population.