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Published on: February 18, 2022
Heart failure in the ethnic minorities
1Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, Canada. moeg@smh.toronto.on.ca
Insights
Heart failure presents differently across ethnic minority groups, with varied causes and risk factors. Understanding these differences is crucial for effective treatment and future research in diverse populations.
Area of Science:
- Cardiology
- Public Health
- Genetics
Background:
- Ethnic minority populations are growing in Western countries.
- Heart failure (HF) prevalence is increasing globally, causing significant morbidity and mortality.
- Limited data exists on HF within ethnic minority groups.
Purpose of the Study:
- To review existing data on heart failure in ethnic minority populations.
- To highlight ethnic variations in HF causes, prevalence, and treatment response.
Main Methods:
- Literature review of studies focusing on heart failure in various ethnic groups.
- Analysis of epidemiological data and clinical trial findings.
Main Results:
- South Asians: Higher coronary risk factors, leading to earlier HF onset.
- Chinese: Hypertension is a key HF cause; HF with preserved ejection fraction is common.
- African-Americans: Higher HF prevalence, younger onset, less likely due to coronary heart disease; specific treatment benefits noted.
- Aboriginal people: Increased HF prevalence, higher atherosclerosis burden, and reduced healthcare access.
Conclusions:
- Significant ethnic disparities exist in HF etiology and treatment efficacy.
- The increasing diversity of global populations necessitates further research into HF across ethnic groups.
Purpose Of Review:
Ethnic minority groups constitute increasing proportions of the population in western countries. Heart failure is increasingly prevalent worldwide and is associated with significant morbidity and mortality. The purpose of this review is to discuss the limited data on heart failure in the ethnic minority groups.
Recent Findings:
South Asians have more coronary risk factors that may increase the risk for premature coronary heart disease leading to development of heart failure at a younger age. In the Chinese, hypertension remains an important cause of heart failure and recent data suggest that heart failure with preserved systolic function is common. African-Americans have a higher prevalence of heart failure than whites, present with heart failure at younger ages, and heart failure in them is less likely to be due to coronary heart disease. Findings from a randomized controlled trial conducted specifically on African-Americans support the addition of the combination of isosorbide dinitrate and hydralazine to standard medical regimen for black patients with heart failure. Aboriginal people are more likely than nonaboriginal people to have less access to healthcare and to have a higher disease burden for atherosclerosis. Heart failure is more prevalent in aboriginal than in the nonaboriginal counterparts.
Summary:
There are important differences across ethnic groups in the causes of heart failure and response to treatment. Given the likely increasing frequency of heart failure in these populations and an increasingly multiethnic world, additional studies on heart failure across different ethnic groups are warranted.
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