[Sclerosing epithelial fibrosarcoma: a clinico-morphological evaluation of 10 cases]

Sclerosing epithelial fibrosarcoma is a malignant mesenchymal tumor (fibroblastic class). It involved tissues of the legs and trunk in patients aged 31-59 and grew slowly as an infiltrative neoplasm during 6-18 months. Relapse occurred in 20% although no metastases were reported. Tumor consisted of epithelial fibroblasts with light cytoplasm and mononuclei. The latter showed low mitotic activity. Fibroblasts came in clusters, bands and alveolar formations sitting in the fibrous stroma. There were small areas consisting of bundles of spindle-shaped fibroblasts with oval hyperchromatic nuclei. Differentiated analysis of epithelioid fibrosarcoma may also be done by computed microscopy and immunomorphology using other tumor models consisting of light-cytoplasm epitheloid cells, mostly osteosarcoma, clear-cell renal carcinoma, melanoma, synovial sarcoma and clear-cell sarcoma of the tendon sheath and aponeurosis.