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Development of mechanical circulatory support devices in China
Wei Wang1, De-Ming Zhu, Wen-Xiang Ding
1Department of Pediatric Thoracic and Cardiovascular Surgery, Shanghai Children's Medical Center, Shanghai Jiaotong University School of Medicine, Shanghai, China. wangweicpb@yahoo.com
Artificial Organs
|December 22, 2009
Summary
Mechanical circulatory support (MCS) devices are crucial for treating cardiac failure. Research in China is advancing various MCS types, including pulsatile, rotary, and total artificial hearts (TAH), for clinical application.
Area of Science:
- Biomedical Engineering
- Cardiovascular Research
- Medical Device Development
Background:
- Myocardial dysfunction causing low cardiac output syndrome is a significant clinical challenge.
- Mechanical circulatory support (MCS) is a vital treatment for advanced cardiac failure.
- China is actively developing diverse MCS technologies.
Purpose of the Study:
- To review the current landscape of mechanical circulatory support (MCS) device development in China.
- To categorize and describe the different types of MCS devices being researched and developed.
- To highlight the progress and nascent stage of MCS innovation in China.
Main Methods:
- Classification of MCS devices into pulsatile, rotary, and total artificial heart (TAH) categories.
- Description of specific device types, including pneumatic pulsatile pumps (Luo-Ye pump), push-plate left ventricular devices, axial and centrifugal rotary pumps (maglev principle), and a TAH.
- Review of clinical application status, from short-term use to laboratory and animal experimentation.
Main Results:
- Several types of pulsatile and rotary MCS devices have been developed, with some already in clinical use.
- Total implantable pumps and a unique TAH design incorporating axial pumps have been engineered.
- While development is in its early stages, a variety of MCS devices are under active investigation in China.
Conclusions:
- China is making progress in developing a range of mechanical circulatory support devices.
- The research encompasses various technologies, from established pulsatile pumps to novel rotary and total artificial heart designs.
- Continued research and development are expected to advance the clinical availability of these life-saving technologies.
