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[Identification of the regions of copy number amplification associated with hepatocellular carcinoma]

Shi-guang Zhang1, Ying-tang Gao, Wen-qin Song

  • 1College of Life Science, Nankai University, Tianjin 300071, China.

Zhonghua Zhong Liu Za Zhi [Chinese Journal of Oncology]
|December 22, 2009
PubMed
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Sequencing of the human genome has opened up several best-kept secrets of the genome. Scientists have identified thousands of genome variations that exist within a population. These variations can be a single nucleotide or a larger chromosomal variation.
Copy number variations or CNVs are the structural variations that cover more than 1kb of DNA sequence. The single nucleotide polymorphism (SNP), on the other hand, is a single nucleotide change or a point mutation that is found in more than 1%...