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Updated: Jun 17, 2026

Skin Biopsy for Diagnosing Discoid Lupus Erythematosus

Skin Biopsy for Diagnosing Discoid Lupus Erythematosus

Published on: June 10, 2025

Verrucous systemic lupus erythematosus.

Ljubka Miteva¹, Valentina Broshtilova, Robert A Schwartz

¹Department of Dermatology and Venereology, Medical University, 1 G. Sofiisky Str., 1431 Sofia, Bulgaria. lubka_miteva@abv.bg

Acta Dermatovenerologica Croatica : ADC

|December 22, 2009

Summary

This summary is machine-generated.

Verrucous lupus erythematosus is a rare variant of systemic lupus erythematosus presenting as painful, hyperkeratotic plaques. Systemic corticosteroids effectively treated a patient with this condition.

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Skin Biopsy for Diagnosing Discoid Lupus Erythematosus

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Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus

Published on: May 16, 2025

Area of Science:

Dermatology
Rheumatology

Background:

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease.
Verrucous (hypertrophic) lupus erythematosus is an uncommon clinical manifestation of SLE.

Observation:

A 29-year-old woman with a 7-year history of SLE presented with painful verrucous plaques on her nose.
Lesions included erythematous, raised, indurated, hyperkeratotic plaques on the nose, toes, and fingers.

Findings:

The characteristic lesion was a large, dull-red, indurated plaque with rolled borders on the nasal bridge.
Histopathological features, though not detailed, are implied to be consistent with verrucous lupus erythematosus.

Implications:

Verrucous lupus erythematosus can mimic other skin conditions like actinic keratosis, keratoacanthoma, and squamous cell carcinoma.
Prompt diagnosis and treatment with systemic corticosteroids can lead to rapid therapeutic effects.