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Updated: Jun 17, 2026

A Patient-Derived Xenograft Model for Venous Malformation
Published on: June 15, 2020
[Infantile vascular tumors].
R López Almaraz1, J C López Gutiérrez, C Belendez Bieler
1Oncohematología Pediátrica, Hospital Universitario de Canarias, La Laguna, Tenerife, España. rlopez@huc.canarias.org <rlopez@huc.canarias.org>
Accurate terminology and diagnosis of pediatric vascular tumors are crucial for effective treatment. This review clarifies classification, characteristics, and management of these diverse lesions.
Area of Science:
- Vascular Medicine
- Pediatric Oncology
- Dermatology
Context:
- Imprecise past terminology for vascular tumors led to misdiagnosis and inadequate treatment.
- Pediatric vascular tumors encompass various types, with infantile hemangiomas being most common.
- Accurate diagnosis is essential for appropriate patient management.
Purpose:
- To review the historical evolution, nomenclature, and classification of vascular lesions.
- To detail the clinical and pathological characteristics of different pediatric vascular tumors.
- To highlight current diagnostic and treatment options for vascular tumors.
Summary:
- Vascular tumors in children require precise diagnosis, distinguishing between common infantile hemangiomas and rarer types like congenital hemangiomas (RICH/NICH), kaposiform hemangioendothelioma, angioblastoma, and pyogenic granuloma.
- Correctly identifying these lesions through multidisciplinary evaluation minimizes diagnostic errors and unnecessary procedures.
- This article provides a comprehensive overview of vascular tumor classification, diagnostics, and therapeutic strategies.
Impact:
- Improved diagnostic accuracy for pediatric vascular tumors.
- Reduced incidence of misdiagnosis and inappropriate treatment.
- Enhanced understanding of vascular lesion management for clinicians.
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