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Primary central nervous system T-cell lymphoma. Case report.

M M Bednar1, A Salerni, M E Flanagan

  • 1Department of Surgery (Division of Neurosurgery), University of Vermont, Burlington.

Journal of Neurosurgery
|April 1, 1991
PubMed
Summary

Primary central nervous system T-cell lymphoma is a rare diagnosis. This case report details a cerebellar T-cell lymphoma, successfully treated with surgery and radiation, with the patient remaining well long-term.

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Area of Science:

  • Neurology
  • Oncology
  • Immunology

Background:

  • Primary central nervous system (CNS) T-cell lymphoma is an exceptionally rare hematologic malignancy.
  • These lymphomas originate within the brain or spinal cord without evidence of systemic disease at diagnosis.

Observation:

  • This case report presents immunocytochemical evidence of a cerebellar CNS T-cell lymphoma.
  • The patient was diagnosed with this rare condition affecting the cerebellum.

Findings:

  • The patient underwent surgical resection followed by radiation therapy.
  • The treatment resulted in a positive outcome, with the patient alive and well 36 months postoperatively.

Implications:

  • This case contributes to the understanding of primary CNS T-cell lymphoma, a rare entity.

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  • It highlights successful management strategies involving surgery and radiation therapy.
  • The report reviews clinical, pathological, diagnostic, and therapeutic aspects, alongside a compilation of prior cases.