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Subthreshold Autism Spectrum in a Patient with Anorexia Nervosa and Behçet's Syndrome.
L Dell'Osso1, B Carpita1, I M Cremone1
1Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy.
Case Reports in Psychiatry
|July 2, 2020
Summary
This study highlights autistic traits in a male patient with anorexia nervosa and Behçet's syndrome, suggesting a link beyond females. It indicates a deeper connection between neurodevelopmental and immune system issues in the autism spectrum.
Area of Science:
- Neuroscience
- Psychiatry
- Immunology
Background:
- Research increasingly notes autistic traits in psychiatric conditions.
- Anorexia nervosa (AN) is frequently linked to the autism spectrum, especially in females, leading to hypotheses of AN as a female autism spectrum disorder (ASD) phenotype.
- Individuals with ASD exhibit higher rates of immune diseases and altered immune functions.
Observation:
- This report details autistic traits in a male inpatient diagnosed with AN, separation anxiety disorder, and Behçet's syndrome (BS).
Findings:
- The case supports the association between AN and the autism spectrum, extending beyond female samples.
- It suggests a significant link between neurodevelopmental and immune system alterations within the broader autism spectrum.
- The findings underscore the need for further investigation into subthreshold autistic manifestations and immune system interactions.
Implications:
- The case challenges the notion of AN as exclusively a female ASD phenotype.
- It points to a potential shared neurobiological pathway involving immune dysregulation in both ASD and AN.
- Further research is warranted to explore the psychopathological and neurobiological underpinnings of these complex associations.
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