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Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
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Naphthalimide gold(I) phosphine complexes as anticancer metallodrugs

Christoph P Bagowski1, Ya You, Heike Scheffler

  • 1Department of Integrative Zoology, Institute of Biology, University of Leiden, 2333 AL Leiden, The Netherlands.

Dalton Transactions (Cambridge, England : 2003)
|December 22, 2009
PubMed
Summary

New gold(I) phosphine complexes with naphthalimide ligands show strong anticancer activity and antiangiogenic effects. These compounds increase cellular gold uptake and exhibit promising potential for cancer drug development.

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