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Updated: Jun 17, 2026

Non-fluoroscopic Catheter Tracking for Fluoroscopy Reduction in Interventional Electrophysiology
Published on: May 26, 2015
Persistent atrial fibrillation converts to common type atrial flutter during CFAE ablation
Armin Luik1, Matthias Merkel, Tobias Riexinger
1IV. Medizinische Klinik des Staedtischen Klinikums, Karlsruhe, Germany. luik@klinikum-karlsruhe.de
Catheter ablation for persistent atrial fibrillation (AF) can be complex. Ablating complex fractionated atrial electrograms (CFAE) in the left atrium sometimes triggers right atrial flutter.
Area of Science:
- Electrophysiology
- Cardiac Arrhythmias
- Minimally Invasive Cardiac Procedures
Background:
- Catheter ablation for persistent and long-standing persistent atrial fibrillation (AF) remains a clinical challenge.
- Current ablation strategies include pulmonary vein isolation, linear lesions, and complex fractionated atrial electrograms (CFAE) ablation.
- Left atrial (LA) tachycardia is a known complication during CFAE ablation, but right atrial flutter is less documented.
Observation:
- This report details three patients undergoing ablation for symptomatic persistent AF.
- During CFAE ablation in the left atrium, a notable electrophysiological shift was observed.
Findings:
- In all three cases, atrial fibrillation (AF) transformed into cavotricuspid isthmus-dependent right atrial flutter.
- This transformation occurred specifically during the ablation of CFAE within the left atrium.
Implications:
- The findings highlight a less-described complication of CFAE ablation in persistent AF.
- Understanding this transition is crucial for refining ablation strategies and improving patient outcomes.
- Further research may elucidate the mechanisms driving this electrophysiological change during AF ablation.
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