Response Surface Methodology
One-Compartment Open Model: Wagner-Nelson and Loo Riegelman Method for ka Estimation
Pharmacodynamic Models: Additive and Proportional Drug Effect Model
Mechanistic Models: Compartment Models in Individual and Population Analysis
Pharmacodynamic Models: Direct Effect Model and Indirect Response Model
Parametric Survival Analysis: Weibull and Exponential Methods
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1Pennsylvania State University, PA, USA. loken@psu.edu
The four-parameter item response theory model (4PM) offers improved fit and more accurate trait inferences than the 3-parameter or 2-parameter models, especially at the extremes of the trait continuum.
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