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Updated: Jun 17, 2026

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
[Radiation therapy and medical imaging]
O Berges1, F Dhermain, F Bidault
1Institut Gustave-Roussy, Service de radiodiagnostic, Villejuif, France.
Advanced imaging techniques improve radiation therapy by precisely targeting tumors and minimizing damage to healthy tissues. This enhances treatment planning and patient safety during radiotherapy delivery.
Area of Science:
- Medical Physics
- Oncology
- Radiology
Background:
- Radiation therapy aims to maximize tumor dose while sparing normal tissues.
- Technological advancements like conformal radiotherapy and intensity-modulated radiotherapy (IMRT) have improved dose distribution.
- Accurate imaging is crucial for adapting radiation plans to individual patient anatomy.
Purpose of the Study:
- To review the role of various imaging modalities in radiation therapy planning and delivery.
- To illustrate how advanced imaging techniques can optimize treatment outcomes.
- To discuss the integration of imaging for real-time patient motion management during treatment.
Main Methods:
- Review of established and emerging imaging techniques in radiation oncology.
- Discussion of morphological and functional imaging applications.
- Exploration of imaging devices integrated with linear accelerators.
Main Results:
- Morphological imaging (e.g., computed tomography) is standard for radiotherapy planning.
- Functional imaging (e.g., MRI, positron emission tomography) offers complementary information.
- 4D computed tomography and integrated imaging systems aid in motion management and adaptive planning.
Conclusions:
- Advanced imaging is integral to modern radiation therapy, enhancing precision and safety.
- Multimodality imaging approaches improve tumor delineation and organ-at-risk identification.
- Continuous imaging during treatment delivery is essential for managing patient motion and ensuring accurate dose application.
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