Catheter-based treatment of coronary artery disease: past, present, and future

David R Holmes1, David O Williams

  • 1Mayo Clinic, Rochester, MN 55901, USA. holmes.david@mayo.edu

Insights

Percutaneous coronary intervention has revolutionized cardiovascular care, becoming the leading worldwide procedure for coronary revascularization. Continuous innovation and technical advancements drive its expanding role in treating heart disease.

Area of Science:

  • Cardiovascular Medicine
  • Interventional Cardiology
  • Medical Technology

Background:

  • The 30-year anniversary of the first human percutaneous coronary intervention (PCI) in September 2007 highlights its transformative impact.
  • Prior to PCI, adult invasive cardiology primarily involved diagnostic angiography and hemodynamic assessment.
  • Coronary revascularization procedures were limited before the advent of PCI.

Purpose of the Study:

  • To review the evolution and impact of percutaneous coronary intervention (PCI) in cardiovascular care.
  • To identify key factors contributing to the widespread adoption of PCI.
  • To emphasize the ongoing importance of innovation in interventional cardiology.

Main Methods:

  • Historical review of interventional cardiology practices.
  • Analysis of factors driving the paradigm shift towards PCI.
  • Discussion of technological advancements and collaborative efforts.

Main Results:

  • Percutaneous coronary intervention (PCI) is now the most frequently performed coronary revascularization procedure globally.
  • Technical improvements and innovation have been pivotal in the success and adoption of PCI.
  • Collaboration among professionals, societies, and industry has accelerated progress.

Conclusions:

  • PCI has fundamentally altered cardiovascular care, establishing itself as a cornerstone treatment.
  • Continued innovation and technical refinement are crucial for advancing PCI.
  • Future developments in technology will expand PCI's application to a wider patient population.

Related Concept Videos

Coronary Artery Disease V: Interprofessional Care01:27

Coronary Artery Disease V: Interprofessional Care

Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
Cardiac Catheterization I: Pre-Procedure Overview01:28

Cardiac Catheterization I: Pre-Procedure Overview

Cardiac catheterization is an invasive diagnostic technique used to identify and evaluate structural and functional diseases of the heart and major blood vessels. This technique diagnoses congenital heart disease, coronary artery disease, valvular heart disease, and coronary spasms and assesses ventricular function. It helps guide treatment decisions, including the need for revascularization procedures like percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) and...
Acute Coronary Syndrome IV: Interprofessional Care01:28

Acute Coronary Syndrome IV: Interprofessional Care

IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
Cardiac Catheterization III: Left Heart Catheterization01:24

Cardiac Catheterization III: Left Heart Catheterization

Left heart catheterization is an invasive diagnostic procedure used to evaluate the function and structure of the left side of the heart. It is generally performed to diagnose and treat cardiovascular conditions such as valve abnormalities, coronary artery disease, and congenital heart defects.Diagnostic and therapeutic purposesLeft heart catheterization serves various diagnostic and therapeutic purposes, including:Assessing coronary artery bypass grafts.Evaluating coronary artery disease in...
Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
Angina IV: Management01:26

Angina IV: Management

IntroductionThe management of angina requires a comprehensive approach that includes pharmacological therapies, medical procedures, and lifestyle modifications.Pharmacological TherapiesAntiplatelet agents, such as aspirin, clopidogrel, prasugrel, and ticagrelor, play a pivotal role in preventing thrombus formation in patients with angina. These medications inhibit platelet aggregation and reduce the likelihood of myocardial infarction and other cardiovascular events.Anticoagulants, including...