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Updated: Jun 17, 2026

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
Catheter-based treatment of coronary artery disease: past, present, and future
David R Holmes1, David O Williams
1Mayo Clinic, Rochester, MN 55901, USA. holmes.david@mayo.edu
Insights
Percutaneous coronary intervention has revolutionized cardiovascular care, becoming the leading worldwide procedure for coronary revascularization. Continuous innovation and technical advancements drive its expanding role in treating heart disease.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Medical Technology
Background:
- The 30-year anniversary of the first human percutaneous coronary intervention (PCI) in September 2007 highlights its transformative impact.
- Prior to PCI, adult invasive cardiology primarily involved diagnostic angiography and hemodynamic assessment.
- Coronary revascularization procedures were limited before the advent of PCI.
Purpose of the Study:
- To review the evolution and impact of percutaneous coronary intervention (PCI) in cardiovascular care.
- To identify key factors contributing to the widespread adoption of PCI.
- To emphasize the ongoing importance of innovation in interventional cardiology.
Main Methods:
- Historical review of interventional cardiology practices.
- Analysis of factors driving the paradigm shift towards PCI.
- Discussion of technological advancements and collaborative efforts.
Main Results:
- Percutaneous coronary intervention (PCI) is now the most frequently performed coronary revascularization procedure globally.
- Technical improvements and innovation have been pivotal in the success and adoption of PCI.
- Collaboration among professionals, societies, and industry has accelerated progress.
Conclusions:
- PCI has fundamentally altered cardiovascular care, establishing itself as a cornerstone treatment.
- Continued innovation and technical refinement are crucial for advancing PCI.
- Future developments in technology will expand PCI's application to a wider patient population.
Abstract:
September 2007 marked the 30-year anniversary of the first human percutaneous coronary intervention, an index event that changed the course of modern-day cardiovascular care. Before that first procedure, adult invasive cardiology focused on diagnostic angiography as well as hemodynamic assessment of structural heart disease. Since that initial procedure, percutaneous coronary intervention has become the most frequently performed coronary revascularization procedure worldwide. Several factors have been responsible for this dramatic paradigm shift, the most prominent being identification of opportunities for technical improvement and the application of innovation and investigation in concert with colleagues, professional societies, and industry. These approaches will continue to be of paramount importance as new technologies are brought to bear on an increasingly broader group of patients with cardiovascular disease.
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