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The secretory phase of the menstrual cycle, spanning from day 14 to 28 in a typical 28-day cycle, is a period of significant physiological changes in the female reproductive system. This phase commences immediately after ovulation and is characterized by the preparation of the endometrium for potential embryo implantation.
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Related Experiment Video

Updated: Jun 17, 2026

Remote Neuronal Activation Coupled with Automated Blood Sampling to Induce and Measure Circulating Luteinizing Hormone in Mice

Remote Neuronal Activation Coupled with Automated Blood Sampling to Induce and Measure Circulating Luteinizing Hormone in Mice

Published on: August 25, 2023

Luteal-phase endocrinology.

I E Messinis¹, C I Messini, K Dafopoulos

¹Department of Obstetrics and Gynaecology, University of Thessalia, Medical School, 41110 Larissa, Greece. messinis@med.uth.gr

Reproductive Biomedicine Online

|December 26, 2009

Summary

This summary is machine-generated.

The corpus luteum, crucial for pregnancy, relies on luteinizing hormone (LH). Ovulation induction suppresses LH, disrupting corpus luteum function and potentially impacting fertility.

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Last Updated: Jun 17, 2026

Remote Neuronal Activation Coupled with Automated Blood Sampling to Induce and Measure Circulating Luteinizing Hormone in Mice

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Published on: August 25, 2023

Frequent Tail-tip Blood Sampling in Mice for the Assessment of Pulsatile Luteinizing Hormone Secretion

Frequent Tail-tip Blood Sampling in Mice for the Assessment of Pulsatile Luteinizing Hormone Secretion

Published on: July 4, 2018

Area of Science:

Reproductive Endocrinology
Gynecology
Cellular Biology

Background:

The corpus luteum is essential for the menstrual cycle and early pregnancy.
Luteinizing hormone (LH) is the primary hormone regulating corpus luteum function.
Ovarian steroids and local factors also influence luteal activity.

Purpose of the Study:

To investigate the impact of ovulation induction on corpus luteum function.
To analyze the role of suppressed LH secretion in luteal phase defects.
To understand the interplay between ovarian steroids and LH in assisted reproductive cycles.

Main Methods:

Review of hormonal profiles during ovulation induction cycles.
Analysis of luteal phase markers and corpus luteum lifespan.
Correlation of LH suppression with luteal function.

Main Results:

Ovulation induction protocols significantly suppress endogenous LH secretion.
Marked LH suppression leads to impaired corpus luteum function.
This disruption occurs irrespective of the specific ovulation induction treatment used.

Conclusions:

Suppressed LH secretion during ovulation induction is detrimental to corpus luteum function.
This hormonal imbalance may contribute to luteal phase defects in assisted reproduction.
Further research is needed to optimize ovulation induction protocols to support luteal function.