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Related Experiment Video

Updated: Jun 17, 2026

Herbs-Partitioned Moxibustion on the Navel in a Rat Model of Primary Dysmenorrhea with Cold Coagulation and Blood Stasis

Herbs-Partitioned Moxibustion on the Navel in a Rat Model of Primary Dysmenorrhea with Cold Coagulation and Blood Stasis

Published on: October 4, 2024

Menstrual disturbances in puberty.

Efthimios Deligeoroglou¹, Pandelis Tsimaris

¹Division of Pediatric - Adolescent Gynecology & Reconstructive Surgery, 2nd Dept Ob/Gyn University of Athens, Aretaieion Hospital 76, Vas. Sophias Av. (115 28) Athens, Greece. edeligeo@aretaieo.uoa.gr

Best Practice & Research. Clinical Obstetrics & Gynaecology

|December 26, 2009

Summary

This summary is machine-generated.

Menstruation onset typically occurs around 12-13 years in girls. Delayed puberty, precocious puberty, and amenorrhoea can arise from various hormonal and anatomical issues, impacting adolescent reproductive health.

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Herbs-Partitioned Moxibustion on the Navel in a Rat Model of Primary Dysmenorrhea with Cold Coagulation and Blood Stasis

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Determination of Reproductive Competence by Confirming Pubertal Onset and Performing a Fertility Assay in Mice and Rats

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Published on: October 13, 2018

Area of Science:

Gynecology
Pediatric Endocrinology

Background:

Menarche, the onset of menstruation, usually occurs between 12 and 13 years of age in adolescent girls.
Variations in pubertal development include precocious puberty (early onset) and delayed puberty (absence by age 14).
Amenorrhoea, the absence of menstruation, stems from diverse causes including anatomical defects and hormonal imbalances.

Purpose of the Study:

To review the common causes and presentations of menstrual irregularities in adolescent girls.
To highlight the significance of abnormal uterine bleeding (AUB) and dysmenorrhoea as urgent and frequent gynecological concerns.

Main Methods:

Review of literature on adolescent menstrual disorders.
Categorization of amenorrhoea causes: hypogonadotrophic hypogonadism, hypergonadotrophic hypogonadism, hyperprolactinaemia, and hypothalamic dysfunction due to stress.
Identification of AUB and dysmenorrhoea as key adolescent gynecological issues.

Main Results:

Amenorrhoea can result from hypogonadotrophic hypogonadism (impaired gonadotrophin secretion), hypergonadotrophic hypogonadism (poor ovarian response), hyperprolactinaemia, and stress-induced hypothalamic dysfunction.
Abnormal uterine bleeding (AUB), particularly dysfunctional uterine bleeding (DUB), represents a critical gynecological emergency in adolescence.
Dysmenorrhoea is the most prevalent gynecological complaint leading to medical consultation among adolescents.

Conclusions:

Understanding the spectrum of menstrual irregularities, from precocious to delayed puberty and amenorrhoea, is crucial for adolescent health.
Prompt diagnosis and management of conditions like AUB and dysmenorrhoea are essential for addressing urgent and frequent gynecological problems in adolescent girls.