Related Experiment Video
Updated: Jun 17, 2026

Extinction Training During the Reconsolidation Window Prevents Recovery of Fear
Published on: August 24, 2012
The temporal specificity of the switch from NMDAr-dependent extinction to NMDAr-independent re-extinction
Julia M Langton1, Rick Richardson
1School of Psychology, University of New South Wales, Sydney, NSW, Australia. jlangton@psy.unsw.edu.au
Abstract:
Recent findings show that the switch from NMDAr-dependent extinction to NMDAr-independent re-extinction is both context and stimulus specific. In this study we examined whether this switch was temporally specific as well. Re-extinction was found to be NMDAr-independent when it occurred 2 days after initial extinction but NMDAr-dependent when it occurred 21 days following initial extinction, thereby illustrating the importance of time as a type of context that modulates the mechanisms involved in extinction.
Related Concept Videos
Long-term Depression
Calcium Ion Concentration Mechanism
If over time, all...
Long-term Depression

