[A case of adenosquamous carcinoma of the liver]

A 60-year-old man underwent abdominal computed tomography due to the chest pressure. Then, a 10 cm sized tumor in the right lobe of the liver was detected. Tumor marker was normal except that CA19-9 was as high as 703 U/mL. We diagnosed as the CCC and performed PTPE, and then, we performed right hepatectomy and adrenal deprivation, and partial resection of the diaphragm and IVC. Pathological diagnosis of the resected specimen was adenosquamous carcinoma of the liver. Metastasis to the costal bone was detected after the operation, and irradiation was performed. Now, S-1/GEM therapy as adjuvant chemotherapy is administered. Adenosquamous carcinoma of the liver is very rare and its prognosis is very poor due to local recurrence and metastasis to the lymph node. Adjuvant therapy is necessary but a unified guideline is not determined.