[Infra-red spectrometry in oral liquid study for diagnostic purposes]

Area of Science:

• Biochemistry
• Spectroscopy
• Medical Diagnostics

Background:

• Infra-red (IR) spectrometry is a valuable tool for analyzing molecular composition.
• Understanding the spectral properties of biological fluids like saliva is crucial for diagnostics.

Purpose of the Study:

• To investigate the utility of IR spectrometry for characterizing saliva.
• To establish quantitative measures for saliva analysis using IR spectral data.

Main Methods:

• Utilized a specialized hardware-software complex for IR spectrometry of saliva.
• Analyzed transmittance fluctuations across 9 distinct IR spectrum ranges.
• Employed multidimensional analysis, including Mahalanobis distance and Bartlett's criteria, for quantitative characterization.

Main Results:

• Observed diverse transmittance fluctuations in 9 IR spectrum ranges, indicating intermolecular interactions.
• Quantified these fluctuations using the dispersion of transmittance coefficients.
• Demonstrated the ability to quantitatively characterize biological fluid states based on spectral data.

Conclusions:

• IR spectrometry provides a quantitative method for analyzing saliva composition.
• The characterized spectral fluctuations hold potential for diagnostic purposes.
• This approach offers a novel way to assess the state of biological liquids.