[Specific ototoxic effects of monomycin in immature animals]
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The Mouse Round-window Approach for Ototoxic Agent Delivery: A Rapid and Reliable Technique for Inducing Cochlear Cell Degeneration
Published on: November 26, 2015
Vestnik Otorinolaringologii
|December 29, 2009
Abstract:
Dynamics of the hearing function was evaluated using immature animals based on the SSCP data. Morphological characteristics of the cochlear auditory ganglion were studied after administration of therapeutic doses of the ototoxic antibiotic monomycin. Untreated animals served as controls. The results of morphofunctional investigations were evaluated in comparison with the similar data obtained in adult cats after injection of the same doses of monomycin.
