Related Experiment Video
Updated: Jun 17, 2026

Capillary Electrophoresis Mass Spectrometry Approaches for Characterization of the Protein and Metabolite Corona Acquired by Nanomaterials
Published on: October 27, 2020
Clinical chemistry: challenges for analytical chemistry and the nanosciences from medicine
1Universitätsklinikum München, Institut für Klinische Chemie, Ludwig-Maximilians-Universität München, Marchioninistrasse 15, 81377 München. juergen.durner@med.uni-muenchen.de
Abstract:
Clinical chemistry and laboratory medicine can look back over more than 150 years of eventful history. The subject encompasses all the medicinal disciplines as well as the remaining natural sciences. Clinical chemistry demonstrates how new insights from basic research in biochemical, biological, analytical chemical, engineering, and information technology can be transferred into the daily routine of medicine to improve diagnosis, therapeutic monitoring, and prevention. This Review begins with a presentation of the development of clinical chemistry. Individual steps between the drawing of blood and interpretation of laboratory data are then illustrated; here not only are pitfalls described, but so are quality control systems. The introduction of new methods and trends into medicinal analysis is explored, along with opportunities and problems associated with personalized medicine.
Related Concept Videos
Development of Analytical Methods
Automated Microbial Diagnostics
Sample Preparation for Analysis: Overview
Bulk or large solid samples are typically reduced in size using grinding, crushing, or milling techniques to increase the...
Data Validation
Key parameters for method validation include:

