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Microsaccadic flutter

J Ashe1, T C Hain, D S Zee

  • 1Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, Maryland.

Insights

Microsaccadic flutter, a rare eye movement disorder, was observed in 5 patients. This condition involves rapid, small, involuntary horizontal eye movements, likely caused by brainstem neuron dysfunction.

Area of Science:

  • Ophthalmology
  • Neuroscience
  • Neurology

Background:

  • Microsaccadic flutter is a rare symptomatic saccadic oscillation.
  • Previous reports documented this rare disorder only twice.

Observation:

  • This study describes 5 new patients diagnosed with microsaccadic flutter.
  • The oscillation is characterized by horizontal movements with a frequency of 15-30 Hz and amplitude of 0.1-0.5 degrees.
  • These movements are sub-visible to the unaided eye and typically not linked to other neurological conditions.

Findings:

  • The observed microsaccadic flutter in 5 patients aligns with previous limited descriptions.
  • The consistent characteristics suggest a specific pathophysiological mechanism.

Implications:

  • The findings expand the known cases of microsaccadic flutter, aiding in its recognition.
  • The hypothesis suggests a potential link between brainstem omnipause neuron malfunction and this ocular motor disorder.
  • Further research into brainstem circuitry could elucidate the etiology of microsaccadic flutter.

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