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Make an M-PACT on asthma: rapid identification of persistent asthma symptoms in a pediatric emergency department
Esther Maria Sampayo1, Amber Chew, Joseph J Zorc
1Division of Emergency Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA 19104-4399, USA. sampayo@email.chop.edu
Insights
A brief, 3-item screen effectively identifies persistent asthma symptoms in children treated in emergency departments (EDs). Most children screened continue to experience symptoms and reduced quality of life one month post-visit, indicating a need for further interventions.
Area of Science:
- Pediatric Emergency Medicine
- Respiratory Medicine
- Clinical Assessment Tools
Background:
- Persistent asthma symptoms are a significant concern in children following emergency department (ED) visits.
- Accurate and brief assessment tools are needed to identify these children for appropriate management.
- Current assessment methods may be lengthy or less sensitive in a fast-paced ED setting.
Purpose of the Study:
- To develop and validate a concise assessment instrument for identifying persistent asthma symptoms in pediatric ED patients.
- To evaluate the sensitivity and predictive value of a brief screen compared to a longer instrument.
- To assess the persistence of symptoms and impact on quality of life one month after ED discharge.
Main Methods:
- A 6-item symptom screen was developed based on national guidelines.
- Parents of children (1-18 years) discharged after acute asthma treatment completed the screen.
- A follow-up phone call 4 weeks later repeated the screen and administered an 8-item asthma-related quality-of-life (ARQOL) instrument.
- Item analysis was performed to refine the screen.
Main Results:
- A 3-item version of the screen, including symptoms with activity, nighttime symptoms, and need for rescue medication, demonstrated 96% sensitivity for detecting persistent symptoms.
- Sixty-nine percent of participants reported persistent symptoms four weeks post-ED visit.
- Children with persistent symptoms exhibited significantly lower ARQOL scores at both baseline and follow-up.
Conclusions:
- A brief, 3-item screen is highly sensitive in identifying persistent asthma symptoms in pediatric ED populations.
- A majority of children treated for acute asthma in the ED continue to experience persistent symptoms and reduced quality of life one month later.
- These findings suggest that pediatric ED patients with persistent symptoms may benefit from additional interventions to improve long-term asthma management.
Objective:
To develop and validate a brief assessment instrument for persistent asthma symptoms in a pediatric emergency department (ED) population.
Methods:
Parents of children aged 1 to 18 years being discharged home after treatment for acute asthma in an urban children's hospital completed a 6-item screen for persistent symptoms that had been developed from national guidelines and previously validated. During a follow-up phone call 4 weeks after the ED visit, the instrument was repeated. An 8-item asthma-related quality-of-life (ARQOL) instrument was also administered at both times to assess construct validity. Item analysis assessed the performance of individual items and their combination versus the full instrument.
Results:
Four hundred thirty-three children were enrolled, and 361 patients (83%) had complete data. Sensitivity and predictive value were calculated for the full screen and combination of items in detecting persistent symptoms at baseline and follow-up. A 3-item version included symptoms with activity, symptoms at night, and need for rescue albuterol. This version was 96% sensitive (95% confidence interval, 92-99) for persistent symptoms compared with the 6-item screen, and 69% (95% confidence interval, 62-76) of the participants continued to report persistent symptoms 4 weeks after the visit. For both screens, subjects with persistent symptoms had significantly worse ARQOL score at baseline and follow-up.
Conclusions:
A brief screen can identify persistent symptoms in pediatric ED patients with good sensitivity compared with a longer instrument. Most of these patients will continue to report persistent symptoms and reduced ARQOL score 1 month after the ED visit and may be candidates for additional interventions in the ED to improve long-term asthma care.
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