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Assessment of the Cytotoxic and Immunomodulatory Effects of Substances in Human Precision-cut Lung Slices
Published on: May 9, 2018
Hypersensitivity pneumonitis: evaluation and management
Lisa Paul1, Stuart G Lehrman, Wilbert S Aronow
1Division of Pulmonary/Critical Care/Sleep Medicine, Department of Medicine, New York Medical College, Valhalla, NY 10595, USA.
Abstract:
Hypersensitivity pneumonitis consists of a group of diseases resulting from inhalation of organic particles causing an immunopathological reaction of the lungs in susceptible individuals. The diagnosis requires a detailed and careful history that would include social, environmental, and occupational status, pulmonary function tests, serum precipitins, bronchoalveolar lavage, imaging, and lung biopsy. Early recognition and avoidance of the causative agent is important although the use of corticosteroids hastens improvement of symptoms.
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