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Incidence and prevalence of common respiratory pathogens before and after implementation of the Cystic Fibrosis

Christy Kim1, Elizabeth delaRiva-Velasco1, Arvind Budhram1

  • 1New York Medical College and Maria Fareri Children's Hospital at Westchester Medical Center Division of Pediatric Pulmonology, Allergy and Sleep Medicine and the Armond V. Mascia Cystic Fibrosis Center, Valhalla, NY, USA.

Journal of Infection Prevention
|February 8, 2020
PubMed

Insights

The 2013 Cystic Fibrosis Foundation

Area of Science:

  • Medical Research
  • Infectious Disease Epidemiology
  • Pulmonology

Background:

  • The Cystic Fibrosis Foundation's Infection Prevention and Control Guideline (CFF IP&C) was established in 2013.
  • The guideline aimed to minimize the risk of respiratory pathogen acquisition and transmission in cystic fibrosis (CF) patients.

Purpose of the Study:

  • To evaluate the impact of the CFF IP&C guideline on the incidence of common respiratory pathogens in CF patients.
  • To test the hypothesis that guideline implementation would decrease pathogen incidence.

Main Methods:

  • A retrospective analysis of respiratory cultures from CF patients between August 2012 and August 2017.
  • Inclusion criteria required at least one culture per year for incidence analysis.
  • Quarterly data were collected for one year pre-guideline and three years post-guideline implementation.

Main Results:

  • No significant changes were observed in the quarterly or annual incidence rates of common respiratory organisms.
  • The prevalence rates of these organisms also remained unchanged during the study period.

Conclusions:

  • The initial three years following CFF IP&C guideline implementation showed no significant effect on the incidence or prevalence of common respiratory pathogens.
  • Further long-term follow-up is necessary to ascertain any delayed effects of the guideline.
Abstract

Keywords:
Cystic fibrosisinfection controlinfection preventionpatient-to-patient transmission

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