Related Experiment Videos
[Has vitamin D(3) dosage improved in Spain? Current levels in a population sample]
Milagros Bernal Pérez1, Giovanna Cortés Flores, Armando Giner Soria
1Sección de Medicina Preventiva y Salud Pública, Hospital Universitario Lozano Blesa, Zaragoza, España. mibernal@unizar.es
Revista Espanola De Geriatria Y Gerontologia
|January 2, 2010
Summary
Vitamin D(3) deficiency has improved in Spain, with 26.8% of the population now having acceptable 25-hydroxyvitamin D(3) levels. This study assessed vitamin D status using RIA-CT, finding improved population levels.
Area of Science:
- Endocrinology
- Nutritional Science
- Clinical Chemistry
Context:
- Current vitamin D(3) classifications suggest widespread deficiency in Spain.
- The metabolite 25-hydroxyvitamin D(3) is crucial for assessing vitamin D status.
- Desirable levels are often considered around 40 ng/ml (100 nmol/l).
Purpose:
- To determine the population status of vitamin D(3) using the RIA-CT technique.
- To evaluate the relationship between distinct diseases and vitamin D(3) deficiency.
- To assess improvements in vitamin D(3) levels within the Spanish population.
Summary:
- A significant improvement in vitamin D(3) levels was observed, with 26.8% of the population now within the acceptable range (10-70 ng/ml).
- The mean 25-hydroxyvitamin D(3) level was 46.2 ng/ml.
- The control group and healthy menopausal women without supplements consistently showed levels of 40 ng/ml or higher.
Impact:
- Suggests a positive shift in public health regarding vitamin D(3) sufficiency.
- Highlights the importance of monitoring 25-hydroxyvitamin D(3) levels for clinical practice.
- Provides updated data on vitamin D(3) status in the Spanish population, informing public health strategies.
Related Concept Videos
Role of Skin in Vitamin D Synthesis
The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin D3(cholecalciferol).
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin D3(cholecalciferol).
Role of Vitamins in Maintaining Bone Health
The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
Study Designs in Epidemiology
Epidemiological study designs are fundamental tools for investigating the distribution, determinants, and control of health conditions in populations. They help researchers understand the relationships between exposures and outcomes, and they broadly fall into two categories: "observational" and "experimental" studies.
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and case-control studies.
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and case-control studies.
Vitamins
Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced in our...
Skeleton and Calcium Homeostasis
Calcium is not only the most abundant mineral in bone but also the most abundant mineral in the human body. Calcium ions are needed for bone mineralization, tooth health, heart rate regulation and strength of contraction, blood coagulation, the contraction of smooth and skeletal muscle cells, and the regulation of nerve impulse conduction. The average calcium level in the blood is about 10 mg/dL. When the body cannot maintain this level, a person will experience hypo or hypercalcemia.
Connective Tissue Cell Types
Connective tissue develops from the mesoderm of a developing embryo and consists of cells, fibers, and ground substance: a gel-like material containing large complexes of carbohydrates and proteins. Connective tissue was first identified as a separate tissue family in the 18th century, and Johannes Peter Muller coined the term connective tissue.
Fat cells (adipocytes), smooth muscle cells (myoblasts), and bone cells (osteoblasts) are some connective tissue cell types. Some immune system cells...
Fat cells (adipocytes), smooth muscle cells (myoblasts), and bone cells (osteoblasts) are some connective tissue cell types. Some immune system cells...