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A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
Published on: January 11, 2020
Midlife predictors of Alzheimer's disease
B B Bendlin1, C M Carlsson, C E Gleason
1William S. Middleton Memorial Veterans Hospital, Geriatric Research Educational and Clinical Center, Madison, WI, USA. bbb@medicine.wisc.edu
None:
Factors contributing to increased risk for Alzheimer's disease (AD) include age, sex, genes, and family history of AD. Several risk factors for AD are endogenous; however, accumulating evidence implicates modifiable risk factors in the pathogenesis of AD. Although the continued task of identifying new genes will be critical to learning more about the disease, several research findings suggest that potentially alterable environmental factors influence genetic contributions, providing targets for disease prevention and treatment. Here, we review midlife risk factors for AD, and address the potential for therapeutic intervention in midlife.
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