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Published on: November 28, 2018
Valve surgery in octogenarians: does it prolong life?
Giulio Rizzoli1, Jonida Bejko, Tomaso Bottio
1Department of Cardiac, Thoracic and Vascular Surgery, University of Padova, Padova, Italy.
Heart valve surgery in octogenarians shows favorable long-term survival rates compared to the general population. These complex operations offer excellent outcomes, even with co-existing health conditions in older adults.
Area of Science:
- Cardiology
- Geriatric Medicine
- Cardiac Surgery
Background:
- Age-related degenerative heart valve disease significantly impacts octogenarians.
- Concomitant diseases in this age group present challenges for valvular replacement therapy.
- Evaluating the risk/benefit of surgical interventions is crucial due to medical, economic, and political factors.
Purpose of the Study:
- To analyze the long-term survival of octogenarians undergoing heart valve operations.
- To compare the survival outcomes of octogenarians with the general population, matched for age, sex, and operative year.
- To assess the efficacy of valvular replacement therapy in the very elderly.
Main Methods:
- Retrospective analysis of 346 octogenarians who underwent 352 heart valve operations between 1987 and 2009.
- Comparison of actuarial survival with a matched general population using US survival rates and Kaplan-Meier plots.
- Detailed recording of heart diseases, pathologies, complications, and survival data.
Main Results:
- Operative mortality was 5.5%, with overall survival at 84.3% (1 year), 65.4% (5 years), 27.3% (10 years), and 5.4% (15 years).
- Octogenarian survival rates favorably compared to expected survival rates of the matched general population (e.g., 27.3% vs. 26.9% at 10 years).
- Female survival rates were slightly higher than males, though not statistically significant (p=0.16).
Conclusions:
- Heart valve operations in octogenarians yield excellent results, outperforming expected survival rates for matched populations.
- Despite higher prevalence of comorbidities, surgical intervention provides favorable outcomes, especially for primary operations.
- Valvular replacement therapy is a viable and effective option for carefully selected octogenarians.
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