Related Experiment Video
Updated: Jun 17, 2026

Video Imaging and Spatiotemporal Maps to Analyze Gastrointestinal Motility in Mice
Published on: February 3, 2016
Recommendations for evaluation and treatment of common gastrointestinal problems in children with ASDs
Timothy Buie1, George J Fuchs, Glenn T Furuta
1Department of Pediatrics, Harvard Medical School, Boston, Massachusetts 02114, USA. tbuie@partners.org
Insights
Pediatric guidelines for diagnosing gastrointestinal issues like abdominal pain and constipation are beneficial for children with autism spectrum disorders (ASDs). Healthcare providers can adapt these for evaluating ASDs patients with GI symptoms, considering behavioral changes.
Area of Science:
- Pediatric Gastroenterology
- Neurodevelopmental Disorders
- Clinical Practice Guidelines
Background:
- Children with autism spectrum disorders (ASDs) frequently experience gastrointestinal (GI) disorders.
- GI symptoms in children with ASDs can manifest as behavioral changes, complicating diagnosis.
- Existing pediatric guidelines offer a framework for evaluating common GI issues.
Framework:
- Adaptation of general pediatric guidelines for abdominal pain, chronic constipation, and gastroesophageal reflux disease (GERD) is recommended.
- These adapted guidelines aid in distinguishing self-limited GI symptoms from those requiring further investigation.
- Focus on thorough medical history and physical examination as initial steps.
Implementation:
- Healthcare providers should consider behavioral manifestations as potential indicators of underlying GI disorders in children with ASDs.
- Utilize established diagnostic approaches for common pediatric GI conditions.
- Document the evaluation process and patient responses carefully.
Implications:
- Current general pediatric guidelines provide a valuable, evidence-informed approach for managing GI symptoms in children with ASDs.
- This strategy supports timely and appropriate care pending the development of ASDs-specific GI guidelines.
- Improved diagnostic accuracy and management of GI disorders can enhance the quality of life for children with ASDs.
Abstract:
Children with autism spectrum disorders (ASDs) can benefit from adaptation of general pediatric guidelines for the diagnostic evaluation of abdominal pain, chronic constipation, and gastroesophageal reflux disease. These guidelines help health care providers determine when gastrointestinal symptoms are self-limited and when evaluation beyond a thorough medical history and physical examination should be considered. Children with ASDs who have gastrointestinal disorders may present with behavioral manifestations. Diagnostic and treatment recommendations for the general pediatric population are useful to consider until the development of evidence-based guidelines specifically for patients with ASDs.
Related Concept Videos
Autism Spectrum Disorder
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
Gastroesophageal Reflux Disease II: Clinical Features and Management
Clinical Manifestations
GERD presents itself in a multitude of ways, with symptoms varying from person to person. The hallmark symptoms are...
Assessment of the Gastrointestinal System I: Subjective Data
Health History
The initial step in assessing the GI system is obtaining a comprehensive health history. This includes inquiring about the patient's history or presence of problems related to...
Irritable Bowel Syndrome III: Medical and Nursing Management
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
Barrett Esophagus-II: Clinical Manifestations and Management
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure entails...
