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Evanescent Field Based Photoacoustics: Optical Property Evaluation at Surfaces

Evanescent Field Based Photoacoustics: Optical Property Evaluation at Surfaces

Published on: July 26, 2016

Nanoparticles for photoacoustic imaging.

Xinmai Yang¹, Erich W Stein, S Ashkenazi

¹Department of Biomedical Engineering, Washington University, St. Louis, MO 63130, USA.

Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology

|January 6, 2010

Summary

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Nanoparticles enhance photoacoustic imaging (PAI) contrast. This review details PAI applications of surface plasmon resonance nanoparticles like gold nanostructures and dye-embedded nanoparticles.

Area of Science:

Biomedical optics
Nanotechnology
Medical imaging

Background:

Nanoparticles serve as contrast agents in optical imaging.
Photoacoustic imaging (PAI) is an emerging hybrid imaging modality.
Nanoparticle contrast agents can improve PAI performance.

Purpose of the Study:

To review the applications of nanoparticles in photoacoustic imaging.
To detail the design and application of various nanoparticle contrast agents for PAI.
To focus on surface plasmon resonance-based nanoparticles and dye-embedded nanoparticles.

Main Methods:

Literature review of nanoparticle applications in PAI.
Analysis of nanoparticle contrast agents based on surface plasmon resonance (gold nanoshells, nanorods, nanocages).

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Evanescent Field Based Photoacoustics: Optical Property Evaluation at Surfaces

Evanescent Field Based Photoacoustics: Optical Property Evaluation at Surfaces

Published on: July 26, 2016

Hand-held Clinical Photoacoustic Imaging System for Real-time Non-invasive Small Animal Imaging

Hand-held Clinical Photoacoustic Imaging System for Real-time Non-invasive Small Animal Imaging

Published on: October 16, 2017

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Three-dimensional Optical-resolution Photoacoustic Microscopy

Published on: May 3, 2011

Review of dye-embedded nanoparticle contrast agents.

Main Results:

Nanoparticles, particularly gold nanostructures, significantly enhance PAI contrast.
Surface plasmon resonance is a key mechanism for nanoparticle-based PAI contrast enhancement.
Dye-embedded nanoparticles offer alternative contrast mechanisms for PAI.

Conclusions:

Nanoparticles are effective contrast agents for photoacoustic imaging.
Gold-based nanoparticles exploiting surface plasmon resonance are prominent in PAI.
Further development of nanoparticle contrast agents will advance PAI capabilities.