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[Bone resorption and formation markers in women with climacteric syndrome in early postmenopause]
Abstract:
The level of bone metabolites and the indices of calcium and phosphorus metabolism were measured in 20 women with climacteric syndrome in postmenopause and in 20 women in premenopause, who had normal bone density and did not differ in the modified risk factors of osteoporosis. In the climacteric women, the normal bone density was accompanied by the elevated levels of CrossLaps and osteocalcin. There was no difference in the concentrations of parathormone, calcium, and phosphorus. After 9-month non-hormonal correction of climacteric syndrome with Estrovel (Ecomir, Russia), the levels of CrossLaps reduced by 45% and that of osteocalcin became normal.
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