Related Experiment Videos
The shoulder in multiple epiphyseal dysplasia
1Victoria Infirmary, Glasgow, Scotland.
The Journal of Bone and Joint Surgery. British Volume
|March 1, 1991
Summary
Multiple epiphyseal dysplasia can affect shoulders, leading to two distinct groups. One group develops osteoarthritis later in life, while the other experiences early movement loss.
Area of Science:
- Orthopedics
- Genetics
- Rheumatology
Background:
- Multiple epiphyseal dysplasia (MED) is a rare genetic disorder affecting bone growth.
- Shoulder involvement in MED can lead to significant morbidity.
Purpose of the Study:
- To characterize the clinical and radiological presentation of shoulder involvement in patients with multiple epiphyseal dysplasia.
- To identify distinct patterns of shoulder disease progression in MED.
Main Methods:
- Assessment of 100 shoulders in 50 patients diagnosed with multiple epiphyseal dysplasia.
- Clinical examination and radiological evaluation to categorize shoulder abnormalities.
Main Results:
- Two distinct groups emerged: those with minor epiphyseal abnormalities and those with 'hatchet head' deformities.
- Minor abnormalities led to osteoarthritis in middle age with preserved movement initially.
- 'Hatchet head' deformities resulted in early and significant loss of glenohumeral movement.
Conclusions:
- Shoulder involvement in MED presents with variable patterns, impacting prognosis and management.
- Early identification of specific radiological patterns may predict disease course and functional limitations.