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Updated: Jun 17, 2026
07:59
A Customizable Approach for the Enzymatic Production and Purification of Diterpenoid Natural Products
Published on: October 4, 2019
[Terpenoids from Euphorbia antiquorum L.]
Yu Chen1, Xue-Jun Tian, Yun-Fang Li
1College of Chemistry and Material Sciences, South Central University for Nationalities, Wuhan 430074, China.
Yao Xue Xue Bao = Acta Pharmaceutica Sinica
|January 9, 2010
Summary
This study isolated seven terpenoids from Euphorbia antiquorum L., including two new diterpenoids and a novel degraded cycloartane triterpenoid, highlighting the plant's diverse chemical constituents.
Area of Science:
- Phytochemistry
- Natural Product Chemistry
Context:
- Euphorbia antiquorum L. is a plant species with potential medicinal properties.
- Understanding its chemical composition is crucial for exploring its pharmacological applications.
Purpose:
- To isolate and identify chemical constituents from the EtOAc extract of Euphorbia antiquorum L.
- To elucidate the structures of isolated compounds using spectroscopic data.
Summary:
- Seven terpenoids were isolated and identified: antiquorine A (1), antiquorine B (2), ent-13S-hydroxy-16-atisene-3,14-dione (3), taraxerol (4), 3beta-hydroxy-25,26,27-trisnorcycloart-24-oic acid (5), 9beta,19-cyclolanostan-3beta-ol (6), and psi-taraxastane-3,20-diol (7).
- Compounds 1 and 2 are new diterpenoids belonging to abietane and ent-kaurane/atisane types, respectively.
- Compound 5 is a new natural product, a degraded cycloartane triterpenoid, and compound 7, a triterpenoid, was isolated for the first time from this plant.
Impact:
- This research expands the knowledge of Euphorbia antiquorum L. chemical diversity.
- The identification of new compounds may lead to further investigations into their biological activities and potential therapeutic uses.
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