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Related Experiment Video

Updated: Jun 17, 2026

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats

Published on: May 22, 2019

Post-stroke depression.

Iris Zavoreo¹, Vanja Basić-Kes, Marijana Bosnar-Puretić

¹University Department of Neurology, Reference Center for Neurovascular Disorders, Ministry of Health and Social Welfare, Republic of Croatia, Sestre milosrdnice University Hospital, Zagreb, Croatia. iris_zavoreo@yahoo.com

Acta Clinica Croatica

|January 9, 2010

Summary

This summary is machine-generated.

Post-stroke depression (PSD) is a common complication affecting stroke recovery and survival. Early recognition and treatment of PSD are crucial for improving outcomes and reducing mortality.

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Effect of Yi-Nao-Jie-Yu Prescription on Post-Stroke Depression in Rats using Middle Cerebral Artery Occlusion Combined with Behavioral Restraint

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Published on: January 9, 2026

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Last Updated: Jun 17, 2026

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats

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Published on: May 22, 2019

Effect of Yi-Nao-Jie-Yu Prescription on Post-Stroke Depression in Rats using Middle Cerebral Artery Occlusion Combined with Behavioral Restraint

Effect of Yi-Nao-Jie-Yu Prescription on Post-Stroke Depression in Rats using Middle Cerebral Artery Occlusion Combined with Behavioral Restraint

Published on: January 9, 2026

Area of Science:

Neurology
Psychiatry
Public Health

Background:

Post-stroke depression (PSD) is a frequent complication following a stroke.
PSD negatively impacts motor and cognitive recovery and increases stroke-related mortality risk.

Purpose of the Study:

To summarize the prevalence, course, and importance of early intervention for post-stroke depression.

Main Methods:

This abstract reviews existing knowledge on post-stroke depression, focusing on its prevalence, temporal patterns, and clinical significance.

Main Results:

PSD prevalence peaks 3-6 months post-stroke, declining over a year but can persist long-term.
Major depression may remit spontaneously within 1-2 years, while minor depression shows variable duration.
Early identification and pharmacological treatment of PSD are vital for better functional outcomes and reduced mortality.

Conclusions:

Post-stroke depression significantly affects patient recovery and survival.
Timely intervention for PSD is essential to mitigate its adverse consequences.