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Candida albicans prosthetic hip infection in elderly patients: is fluconazole monotherapy an option?

Theodoros Kelesidis1, Sotirios Tsiodras

  • 1Department of Medicine, Caritas St. Elizabeth's Medical Center, Tufts University School of Medicine, 736 Cambridge Street, Boston, MA 02135, USA. Theodoros.Kelesidis@caritaschristi.org

Scandinavian Journal of Infectious Diseases
|January 9, 2010
PubMed

Insights

This study presents a rare case of Candida albicans prosthetic hip infection successfully treated with fluconazole monotherapy. This finding suggests fluconazole monotherapy may be a viable option for select patients with fungal prosthetic joint infections.

Area of Science:

  • Infectious Diseases
  • Orthopedic Surgery
  • Mycology

Background:

  • Prosthetic joint infections are increasing due to more joint arthroplasties and sicker patients.
  • Candida prosthetic joint infections are rare, with only 12 cases of Candida albicans prosthetic hip infection documented.
  • Standard treatment involves surgery and prolonged antifungal medication.

Observation:

  • A rare case of Candida albicans prosthetic hip arthritis is reported.
  • The patient was debilitated and elderly, typically not candidates for monotherapy.

Findings:

  • Successful treatment of Candida albicans prosthetic hip arthritis with fluconazole monotherapy.
  • This represents the second reported case of successful fluconazole monotherapy for this condition.

Implications:

  • Fluconazole monotherapy may be a potential therapeutic option for select patients with fungal prosthetic joint infections.
  • Further research is needed to establish the role of fluconazole in managing fungal prosthetic infections.

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