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Updated: Jun 17, 2026
11:47
A Novel in vivo Gene Transfer Technique and in vitro Cell Based Assays for the Study of Bone Loss in Musculoskeletal Disorders
Published on: June 8, 2014
Update in male osteoporosis
1College of Medicine, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA. khosla.sundeep@mayo.edu
The Journal of Clinical Endocrinology and Metabolism
|January 9, 2010
Summary
Male osteoporosis is a growing concern, with one in five men over 50 experiencing fractures. Research reveals ongoing bone loss and highlights estradiol
Area of Science:
- Bone biology and aging
- Men's health
- Osteoporosis research
Background:
- Osteoporosis in men is a significant public health issue.
- Men over 50 face a 1 in 5 risk of osteoporotic fractures.
- Fractures in men are associated with increased mortality.
Purpose of the Study:
- To review current understanding of male osteoporosis.
- To highlight new insights into bone structure and aging in men.
- To discuss evolving diagnostic and management strategies.
Main Methods:
- Literature review utilizing PubMed.
- Incorporation of author expertise in the field.
- Analysis of data from computed tomography and advanced imaging techniques.
Main Results:
- Significant trabecular bone loss occurs in men from young adulthood.
- Serum estradiol levels are key predictors of fracture risk.
- Diagnostic criteria and fracture risk assessment tools are advancing.
Conclusions:
- Male osteoporosis pathogenesis and management still have unresolved issues.
- Public awareness of male osteoporosis needs enhancement.
- Despite advances, further research is critical.
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