Total Internal Reflection Fluorescence Microscopy
Super-resolution Fluorescence Microscopy
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Updated: Jun 17, 2026

High-Throughput Total Internal Reflection Fluorescence and Direct Stochastic Optical Reconstruction Microscopy Using a Photonic Chip
Published on: November 16, 2019
1Radar and Optics Laboratory, Institute of Science and Technology, The University of Michigan, AnnArbor, Michigan 48107, USA.
Researchers created vibrant, three-dimensional multicolor holograms using two and three primary colors from gas lasers. This advanced holographic technique minimizes ghost images, enabling realistic 3D reconstructions with natural hues.
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