Related Experiment Video
Updated: Jun 17, 2026

A New Single Chamber Implantable Defibrillator with Atrial Sensing: A Practical Demonstration of Sensing and Ease of Implantation
Published on: February 28, 2012
Twiddling with an implantable cardioverter-defibrillator
Conor J McCann1, Roel Beelen, Peter Geelen
1Cardiovascular Centre, OLV Hospital, Aalst, Belgium. conorjmccann@hotmail.com
Twiddler's syndrome, a rare complication of implantable cardioverter-defibrillator (ICD) implantation, occurs when patients manipulate the device. This case highlights the importance of lead repositioning and generator relocation to prevent recurrence.
Area of Science:
- Cardiology
- Medical Devices
- Patient Safety
Background:
- Implantation of a single-chamber implantable cardioverter-defibrillator (ICD) in the right ventricular apex.
- Generator placed in a left pre-pectoral pocket.
- Post-implantation monitoring is crucial for device function.
Observation:
- Device interrogation revealed inappropriate sensing and pacing failure 4 weeks after implantation.
- Chest X-ray demonstrated the ICD lead coiled behind the generator.
- Patient self-reported manipulating the implanted device.
Findings:
- Diagnosis of Twiddler's syndrome confirmed.
- Successful lead repositioning performed.
- Generator relocated to a sub-pectoral position to mitigate recurrence.
Implications:
- Twiddler's syndrome can compromise ICD efficacy.
- Preventive strategies include optimizing lead placement and generator pocket choice.
- Patient education on device care is essential to avoid complications.
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