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Updated: Jun 17, 2026

In Vitro Evaluation of Oncogenic Transformation in Human Mammary Epithelial Cells
Published on: September 24, 2020
[Risk evaluation for malignant transformation breast intraductal papilloma]
Aim:
To evaluate the risk evaluation for malignant transformation breast intraductal papiloma.
Materials And Methods:
277 women with pathologic nipple discharge were evaluated and operated on during 1994-2005. Nipple discharge was unilateral in 217 patients and bilateral in 60. The main diagnostic methods were clinical examination, ductography, discharge cytology. Cytologycal test was of greatest evidence. All 277 women were with small multiple papillomes. We found carcinoma in only 3 cases--1 intraductal and 2 invasive ductal carcinomas.
Conclusion:
According to our results 1.1% of our patient were with malignant potential.

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