Related Experiment Video
Updated: Jul 4, 2026

Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma
Published on: April 11, 2018
Abstract:
For a period of 12 years (1994-2005) we operated on 82 patients with malignant neoplasms in the soft tissues. We distributed the patients by the disease stage, localization and histology. Basically the patients underwent CAT, NMR, echography for affected proximate lymph nodes and X-ray of the lungs to check for distal metastases. With 42 of the tumors we performed precursory open biopsy and with 4 of the tumors we performed FNAB. FNAB is a cytological test not able to differentiate the tumor in detail, so subsequently we discontinued its application. 94 surgical operations including only one amputation were performed with 82 of the patients. The main methods of surgical intervention were the extended resections and excisions, but some more serious interventions had to be performed with differentiated localizations, such as the retroperitoneal liposarcomas (where sometimes other organs (kidney) had to be removed), breast sarcomas leading to mastectomies, shoulder area sarcomas requiring humeroscapular resections, stomach angiosarcomas resulting in subtotal resections etc. The histological variant, the tumor size and localization - either anatomical or in depth, are established and reported to be the main aggravating factors. The distinct resection lines during the operation and the presurgery planning after NMR turned out to be a very important prognostication sign. The 5-year survival period reaches 70%.
Related Concept Videos
Treatment Resistant Cancers
Treatment Resistent Cancers
