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Subungual extraskeletal chondroma with finger nail deformity: case report
Takayuki Ishii1, Masayoshi Ikeda, Yoshinori Oka
1Department of Orthopaedic Surgery, Tokai University Hachioji Hospital, Tokyo, Japan.
Abstract:
We report a subungual extraskeletal chondroma with a convex nail deformity originating from the index finger in a 39-year-old man. The tumor was excised and its histopathology showed obvious nuclear pleomorphism. However, the Ki-67 (MIB-1) labeling index was less than 1%, indicating low proliferative activity; it was classified as an extraskeletal chondroma with atypical features. There was no recurrence over a 3-year postoperative period.
Insights
A rare subungual extraskeletal chondroma causing nail deformity was surgically removed. Despite atypical features, low cell proliferation and no recurrence suggest a favorable prognosis for this benign tumor.
Area of Science:
- Orthopedic Surgery
- Oncology
- Dermatopathology
Background:
- Subungual extraskeletal chondromas are rare benign bone tumors.
- Nail deformities can be caused by various subungual pathologies.
Observation:
- A 39-year-old man presented with a subungual extraskeletal chondroma on his index finger, causing a convex nail deformity.
- Surgical excision was performed for the tumor.
Findings:
- Histopathology revealed significant nuclear pleomorphism, indicative of atypical features.
- A low Ki-67 (MIB-1) labeling index (<1%) suggested low proliferative activity.
- The tumor was classified as an extraskeletal chondroma with atypical features.
Implications:
- This case highlights the importance of considering benign tumors in the differential diagnosis of nail deformities.
- Despite atypical histological features, low proliferative activity may predict a favorable clinical outcome.
- Long-term follow-up confirmed no recurrence over a 3-year period, supporting successful management.
