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Related Concept Videos

Pneumothorax-II01:27

Pneumothorax-II

Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:
Pneumothorax-I01:26

Pneumothorax-I

A pneumothorax is a condition where air builds up in the space between the lung and the chest wall, causing the lung to collapse. This condition arises when air enters the space between the parietal and visceral pleura, disrupting the negative pressure essential for lung inflation. This can lead to a partial or complete collapse of the lung.
Pneumothorax can be even further classified as spontaneous, traumatic, and tension pneumothorax.
Pneumothorax II: Pathophysiology01:08

Pneumothorax II: Pathophysiology

Pneumothorax means the presence of air in the pleural space — the thin potential gap between the visceral and parietal pleura. This condition disrupts the normal pressure balance that keeps the lungs inflated, leading to partial or complete collapse of the affected lung.Normal physiologyUnder normal conditions, the pleural space maintains a slightly negative intrapleural pressure, which keeps the lungs expanded against the chest wall. This negative pressure creates a delicate balance between...
Pulmonary Cycle: Exhalation01:17

Pulmonary Cycle: Exhalation

In terms of human respiration, the act of expelling air, known as exhalation (or expiration), operates on the principle of pressure gradients. During expiration, the pressure within the lungs exceeds that of the surrounding atmosphere. Under normal conditions, quiet breathing involves passive exhalation and is free of muscular contractions. This is because the exhalation process is driven by the natural elastic recoil of the lungs and chest wall, both of which have an inherent tendency to...
Atelectasis II: Pathophysiology01:10

Atelectasis II: Pathophysiology

Atelectasis develops when alveoli lose their air and collapse inward. Because lung tissue is naturally elastic, these air sacs shrink rather than remaining open. Collapsed alveoli are no longer ventilated, reducing their role in gas exchange. Blood flow may continue in these regions, creating a ventilation–perfusion mismatch. Clinical findings include decreased breath sounds, dullness to percussion, reduced chest expansion, and decreased tactile fremitus as sound transmission through collapsed...
Flail Chest-II01:26

Flail Chest-II

Managing flail chest, a condition characterized by a segment of the chest wall moving independently from the rest of the thoracic cage, requires a comprehensive approach. It includes a thorough assessment of the patient's condition, a diagnostic evaluation to determine the extent of the injury, and the implementation of appropriate medical interventions tailored to the individual's needs.
Assessment:
1. Clinical Evaluation:
History:

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Related Experiment Video

Updated: Jun 17, 2026

Non-Intubated Video-Assisted Thoracoscopic Surgery
05:39

Non-Intubated Video-Assisted Thoracoscopic Surgery

Published on: May 26, 2023

Acute lung injury after thoracic surgery.

Kenneth D Eichenbaum1, Steven M Neustein

  • 1The Mount Sinai School of Medicine, New York, NY, USA.

Journal of Cardiothoracic and Vascular Anesthesia
|January 12, 2010
PubMed
Summary

Anesthesiologists should suspect acute lung injury (ALI) in thoracic surgery patients. Conservative fluid management and lung-protective ventilation strategies can reduce ventilator days and organ failure.

Area of Science:

  • Anesthesiology
  • Pulmonary Medicine
  • Critical Care Medicine

Background:

  • Acute lung injury (ALI) is a significant concern in the perioperative period, especially after thoracic surgery.
  • Early diagnosis relies on recognizing acute hypoxemia, diffuse infiltrates on imaging, and noncardiogenic pulmonary edema.

Purpose of the Study:

  • To review diagnostic criteria, risk factors, and management strategies for perioperative acute lung injury.
  • To provide guidance for anesthesiologists managing patients at risk for ALI.

Main Methods:

  • Review of existing literature on ALI diagnosis and perioperative management.
  • Discussion of intraoperative and postoperative strategies, including fluid management and mechanical ventilation.

Main Results:

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A Model of Self-limited Acute Lung Injury by Unilateral Intra-bronchial Acid Instillation
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A Model of Self-limited Acute Lung Injury by Unilateral Intra-bronchial Acid Instillation

Published on: August 30, 2019

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A Model of Self-limited Acute Lung Injury by Unilateral Intra-bronchial Acid Instillation
07:40

A Model of Self-limited Acute Lung Injury by Unilateral Intra-bronchial Acid Instillation

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  • Conservative fluid management (neutral to negative balance) can decrease ventilator days.
  • Lung-protective ventilation (low tidal volumes, low plateau pressures) may reduce organ failure.
  • Positive end-expiratory pressure (PEEP) may improve oxygenation but not mortality.

Conclusions:

  • Maintaining a high index of suspicion for ALI is crucial in thoracic surgery.
  • Optimizing fluid balance and employing lung-protective ventilation are key risk-reduction strategies.
  • Further research into biomarkers and pharmacologic agents is needed for improved ALI management.