Related Experiment Video
Updated: Jun 17, 2026

A Ligated Intestinal Loop Model in Anesthetized Specific Pathogen Free Chickens to Study Clostridium Perfringens Virulence
Published on: October 11, 2018
Beta2-toxin of Clostridium perfringens in a hamadryas baboon (Papio hamadryas) with enteritis
Georgios N Nikolaou1, Marja J L Kik, Alphons J A M van Asten
1Department of Pathobiology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.
Abstract:
An 11-yr-old female hamadryas baboon (Papio hamadryas) that died with a history of diarrhea and anorexia was submitted for necropsy. Major pathologic changes were restricted to the gastrointestinal tract. The small intestinal contents were watery and sanguinous, with a deepening of the red color in the large intestines. The intestinal mucosa was hyperemic. Microscopically, lesions consisted of surface epithelial cell necrosis in association with numerous rod-shaped bacteria and high numbers of Trichuris cynocephalus nematodes. Culturing of the small intestine yielded Clostridium perfringens. No other pathogenic bacteria were cultured using routine bacteriologic techniques. Polymerase chain reaction (PCR) analysis classified the Clostridium perfringens as type A cpb2-positive. Immunohistochemical examination with anti-beta2-toxin antibodies revealed beta2-toxin in close approximation with the intestinal lesions.
More Related Videos
06:51Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291
Published on: December 10, 2016
13:12Transsynaptic Tracing from Peripheral Targets with Pseudorabies Virus Followed by Cholera Toxin and Biotinylated Dextran Amines Double Labeling
Published on: September 14, 2015
Related Concept Videos
Bacterial Gastroenteritis
Botulism
Diphtheria
Toxoplasmosis
Acute Pancreatitis II: Pathophysiology
Amebiasis