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Updated: Jun 17, 2026
Quantitative Mass Spectrometric Profiling of Cancer-cell Proteomes Derived From Liquid and Solid Tumors
Published on: February 27, 2015
[Proteomics and biomarkers for detection of cervical cancer]
1Lékarská fakulta Hradec Králové Univerzita Karlova Praha, Porodnická a gynekologická klinika FN Hradec Králové. kacermar@fnhk.cz
Objective:
The purpose of this study was to focus on recent developments in the rapidly evolving field of biomarker discovery and validation techniques using proteomics platform with respect to cervical cancer.
Design:
Review.
Setting:
Department of Obstetrics and Gynecology Medical Faculty Charles University Hradec Kralove.
Methods:
The last decade has seen major changes in the technologies used to identify diagnostic markers for early stages of cervical cancer. Significant advances were achieved in three key areas: protein profilling, multidimensional liquid chromatography combined with cutting edge mass spectrometry and high-throughput validation techniques. These new technologies hold significant promise in identifying more robust, sensitive and specific markers for cervical cancer.
Conclusion:
The present review summarizes the results of clinical and experimental research on biomarkers of cervical cancer.
